Gold for designer DNA architecture

Designer DNA Architectures for Bionanotechnology

Architecture with designer atoms: simple theoretical considerations.

The distinct electronic states of assemblies of metallic quantum dots are discussed in a simple approximation where each dot is mimicked as an "atom" that carries one valence electron. Because of their large size, the charging energy of the dots, I = energy required to add another electron, is much smaller than for ordinary atoms. The Coulomb blocking of charge migration is therefore easier to ...

Nanobiomedicine Designer DNA Architectures : Applications in Nanomedicine

DNA has been used as a material for the construction of nanoscale objects. These nanostructures are programmable and allow the conjugation of biomolecular guests to improve their functionality. DNA nanostructures display a wide variety of characteristics, such as cellular permeabil‐ ity, biocompatibility and stability, and responsiveness to external stimuli, making them excellent candidates for...

Rhodamine Activated Gold Nanoaggregates for Dna Detection

Surface enhanced Raman scattering (SERS) is demonstrating a lot of potentials as a sensitive precious probe for chemical and bioanalitical applications. Since long time, the vibrational spectroscopy provides highly specific chemical information about DNA, RNA, viruses and molecules that makes both FTIR and Raman spectroscopies well suited for “fingerprint” detection in biomedical analysis. Howe...

R2oDNA designer: computational design of biologically neutral synthetic DNA sequences.

R2oDNA Designer is a web application that stochastically generates orthogonal sets of synthetic DNA sequences designed to be biologically neutral. Biologically neutral sequences may be used for directing efficient DNA assembly by overlap-directed methods, as a negative control for functional DNA, as barcodes, or potentially as spacer regions to insulate biological parts from local context. The ...